Below are lists of technologies presented at previous MidWest Drug Development conferences. Technologies are listed according to year and in alphabetic order. Subscribe to get important updates as they happen, or register to join us in 2021!
2019 MWDD
2019 Technology Presentations
| Antibacterials for methicillin, vancomycin resistant bacteria | Mps1 kinase inhibitor as a treatment for solid tumors |
| Antibiotics to treat highly resistant enterococcus | Nanoparticle drug delivery systems |
| Antimicrobial peptides for therapeutics | Nanoparticle-miRNA conjugate reduces inflammation, oxidative stress |
| Antisense oligonucleotides to treat spinal muscular atrophy | New PDE4B selective inhibitors improve inflammatory disease treatments |
| Bacterial glycosyltransferase inhibitors work as anti-virulence compounds | Novel crocetin compound prevents, treats pancreatic cancer |
| CAR-NK therapy for lupus | Novel mithramycin derivatives for cancer chemotherapy |
| CAR T approach could prevent Type 1 diabetes | Novel peptide antagonists for modulating GPCR pharmacology |
| Combine nanoparticles, checkpoint blockade therapy | Peptide-based methods to treat neurological injury, disease |
| Composite biodegradable formulation promotes bone regeneration in diabetics | Preventative therapy treats post-traumatic osteoarthritis |
| DHODH inhibitors to treat hematological malignancies | Protease inhibitor drugs with improved PK, bioavailability |
| Dopaminergic ligands to treat tissue fibrosis | Selective estrogen receptor modulator (ER-Beta agonist) as a new approach to targeting cancer |
| Extended Par-4 protein to treat cancer | SHetA2 combination therapy for cancer |
| Family of small molecule drugs to treat diabetes complications | Small molecule inhibitors of EYA3 to treat cancer, hypertension diabetic retinopathy |
| Fast-acting, reversible neuromuscular blockers | Small molecule inhibitors of NAMPT |
| Furoxans to treat neurodegenerative disorders | Small molecule ligand for PSMA-targeted radioligand therapy |
| GGDPS inhibitors for the treatment of cancer | Small molecule Rac inhibitor as new therapy |
| Glucocorticoid prodrugs for the treatment of nephritis | Small molecule treatment targets lymphoblastic leukemia/lymphoma |
| Harness tissue regeneration to treat ulcers, intractable wounds | Synthetic mimics of malonyl-CoA as fatty acid synthase inhibitors |
| In situ activation of Car T cells for therapy | Treat macular degeneration with cell therapy |
| Kappa opioid receptor antagonists to treat depression, anxiety | Veratridine targets colon cancer cells |
| Low-molecular weight anti-PD-L1 peptide for cancer immunotherapy | VSV cDNA libraries for cancer immuno/virotherapy |
2018 MWDD
2018 Technology Presentations
| Anti-cancer Drugs Based on Natural Compounds | NF-kB Inhibitors |
| Broad Spectrum Antivirals | Non-Invasive Leads for Eye Vascular Disease |
| Carrier-free Nanoparticle Formulation | Non-opioid for Treating Chronic Pain |
| CCL21 Nanoparticles for Cancer Immunotherapy | Novel Anthelmintic Drugs |
| Chemical Agents for Antifungal Applications | Peptides for Treatment of Ischemia/Reperfusion |
| Compounds for the Prevention of Heart Failure | Peptoid cancer drugs targeting PCNA |
| Copper-Activated Antibacterial Drugs | POSH Inhibitor-based Cancer Therapy |
| Delivery Platform for drugs and gene therapy | Prostate Cancer Vaccine |
| Drug Delivery System for Targeting Multiple Myeloma | PVX Broad Spectrum Antiviral |
| Fatty Acid Uptake Inhibitors | Saracatinib for epileptic seizures |
| Gastric pH Control for the Treatment of Acid Reflux | Sensory Neuron Actin Remodeling in Pain |
| Her2 Targeted Antibody Drug Conjugate | SMN2 Catalytic Core for Spinal Muscle Atrophy |
| Histone Deacetylase Inhibitors | Soluble Antigen Arrays for Autoimmune Diseases |
| Hsp90? Selective Inhibitors | Super-antibiotic |
| Immune Stimulating Peptides | Targeting Sigma-2 Receptor for Cancer |
| Influenza Vaccine | Theranostics for Personalized Medicine |
| Long Acting Antiretroviral Formulations | Therapy for the Reversal of Type 1 Diabetes |
| Mps1 Kinase Inhibitors | TR3 Biologics for the Treatment of Cancer |
| Natural Surfactant Helps With ARDS | Water Soluble Glucagon Derivative |
| Neuroprotection by Mitochondria-targeted Metformin |